Titan Quest is a great game with a very long introduction. Once you have seen it several times, you just like to get right to the game. Follow this tech-recipe to bypass the intro.
1. Go to the Video directory in your Titan Quest directory.
2. There are four files here you need to rename: TQCinematic.bik, TQGameIntro.bik, TQLegal.bik, and TQLogos.bik. (You can just add some text to the beginning of the file name like orig_.)
3. Right-click in the directory, and create a text file. Repeat this three more times. Now, go back and rename your blank text files to the original names of the files you changed in Step 2.
4. Close the window, and play the game with no intro.